What does the science say?
Yes, there is a link between hormone imbalances and the gut
The gut microbiome undergoes significant changes in oestrogen dominance, during both perimenopause and menopause, which can impact hormonal balance. In oestrogen dominance, an imbalance in gut bacteria—particularly those involved in oestrogen metabolism—can lead to increased levels of circulating oestrogen. This occurs when bacteria like Enterococcus and Bacteroides produce β-glucuronidase, an enzyme that reactivates oestrogens, allowing them to be recirculated instead of excreted. During perimenopause and menopause, the decline in oestrogen levels leads to shifts in gut microbiota diversity, often resulting in reduced populations of beneficial bacteria like Firmicutes.
Why your stomach hurts?
Emerging research shows a strong connection between digestive issues like constipation, diarrhea, and stomach discomfort with dysbiosis (imbalanced gut bacteria). Studies have found that people with conditions like Irritable Bowel Syndrome (IBS) often experience a disruption in their gut microbiota, leading to reduced diversity and an overgrowth of harmful bacteria.
The Gut-Brain Connection: How microbial imbalances influence mood, focus, and cognitive function
In ADHD-related studies, a unique bacterial profile was observed, often showing reduced levels of Bifidobacterium and Faecalibacterium , which play roles in gut barrier integrity and anti-inflammatory responses. Conversely, an increase in Bacteroides, which has been linked to neuroinflammation, was found in individuals with ADHD. Similarly, in mood disorders such as depression and anxiety, reductions in Lactobacillus and Bifidobacterium—both known for their role in serotonin metabolism and gut-brain signaling—were commonly reported.
Testing can help determine low or an overgrowth of these commensal bacteria.
Fatigue and low energy
Low energy can feel like a relentless fog, draining your zest for life. Dysbiosis might be the sneaky culprit. Research shows that a disrupted gut microbiome messes with energy metabolism by impairing nutrient absorption and ramping up inflammation This gut chaos can tank your mood, zap motivation, and leave you sluggish. Picture it: your gut’s a power plant, and when it’s out of whack, the lights dim on everything—work, play, even basic get-up-and-go. Fix the gut, and you might just recharge your life.
Did you know you can make your own GLP-1?
Glucagon-like peptide-1 (GLP-1) is a gut-derived hormone that’s a rockstar in appetite suppression and blood sugar control. Yet, we often miss its critical gut link. Side-lining the natural gut ecosystem that drives its production, leaving us disconnected from this built-in metabolic maestro. Find out what the key stimulator is of GLP-1 and other appetite regulatory hormones.
